Nolvadex is a hormonal drug that contains an active ingredient such as Tamoxifen. The main function of this drug is to completely or partially block the production of hormones in the body of women and men - estrogen, which, in turn, provoked the formation and growth of tumors in the mammary and breast glands, endometrium, ovaries, kidney cancer, sarcoma soft tissue and melanoma. The active ingredient, Tamoxifen, significantly slows down the growth of tumors in the body. The drug is available in tablets, and you can buy it at the Nolvadex pharmacy after a doctor's recommendation. After taking one pill in the body is able to block the production of estrogen hormone up to 2 weeks. That is, even one tablet contains enough Tamoxifene to stop the production of estrogen for such a long time. Also, do not forget that Nolvadex can cause extravagant ovulation in the female body, so during the use of this medicine is worth taking more careful care of contraception, which in no case should not be hormonal.
Nolvadex is used in the treatment of breast cancer in women, breast cancer in men who have survived castration, oncology of the kidneys or prostate gland. It is prohibited to take the drug if the patient is hypersensitive or intolerant to the active substance Tamoxifene, during pregnancy and during breastfeeding. It is not recommended to take tablets for people suffering from eye diseases, thromboembolic disease and severe thrombophlebitis.
Nolvadex is used inside, drinking water. The standard dose for adults is 20 mg. In the case of a common form of disease, the dose can be increased to 30-40 mg/day. The maximum daily dose is 40 mg. Objective response is usually after 4-10 weeks of therapy, but in the case of metastases in the bones, the therapeutic effect can be observed only after a few months of drug administration. The duration of treatment is determined by the severity and course of the disease. Generally, the treatment is long and lasts until remission is achieved. There is no need to correct the dose in elderly patients, patients with kidney or liver dysfunction.
The drug should not be used during pregnancy. Pregnant women treated with tamoxifene have had isolated cases of spontaneous miscarriage, congenital malformations, and fetal death, but the relationship between these phenomena and tamoxifene is not clearly established. The study of reproductive toxicity in animals did not reveal any teratogenic effect. The study of intrauterine development in animals demonstrated that drug therapy is associated with changes similar to the effects of estradiol, ethinylestradiol, clomiphene, diethyl styllebestrol. Before starting therapy, it is necessary to make sure that the patient is not pregnant. Contraceptives should be used for the entire duration of the therapy and at least 3 months after its completion. Oral contraceptives should not be used. It is not known whether the drug is excreted with breast milk, so during the treatment period breastfeeding is stopped.
During the treatment of Nolvadex should be regularly monitored the level of platelets and calcium in the blood, with prolonged use of the drug Nolvadex shows the observation of an ophthalmologist. During treatment, it is not recommended to perform work requiring increased attention. Do not combine with drugs containing hormones, especially estrogens. In combination with other oncological drugs increases the risk of thrombosis. Nolvadex is a highly effective medicine and should be kept out of the reach of children. Please leave the film-coated tablets in blister packs before use so that they are optimally protected from light and moisture. Do not store film-coated tablets at temperatures above 30°C.